The high-speed and automated drilling and planting machine, designed and developed based on Beckhoff’s TwinCAT bus control, achieves one-time drilling and planting of bristles onto products. The project involves various aspects, including platform five-axis algorithms, electronic cam motion trajectories, and high-speed dynamic cam smooth switching. These elements demonstrate the significant advantages of Beckhoff’s real-time PLC control. By swapping different clamping platforms, this machine can produce various types of products, such as flat brushes, roller brushes, disc brushes, and spherical brushes, all on a single workstation.